/* ==========================================================================
   Calculadora de Función Renal y Aclaramiento de Creatinina (CKD-EPI 2021)
   Fijate Tools - Hoja de estilo canónica
   ========================================================================== */

:root {
  --font-main: 'Inter', system-ui, -apple-system, sans-serif;
  --font-heading: 'Outfit', 'Inter', sans-serif;
  --font-mono: 'JetBrains Mono', monospace;

  /* Modo oscuro por defecto (Midnight Slate) */
  --bg-body: #0b0f17;
  --bg-card: #111827;
  --bg-card-subtle: #162032;
  --bg-input: #1b263b;
  --border-color: #27354a;
  --border-focus: #06b6d4;

  --text-primary: #f8fafc;
  --text-secondary: #cbd5e1;
  --text-muted: #94a3b8;

  --primary-color: #06b6d4;
  --primary-hover: #0891b2;
  --primary-light: rgba(6, 182, 212, 0.15);

  --success-color: #10b981;
  --success-light: rgba(16, 185, 129, 0.15);

  --warning-color: #f59e0b;
  --warning-light: rgba(245, 158, 11, 0.15);

  --danger-color: #ef4444;
  --danger-light: rgba(239, 68, 68, 0.15);

  --purple-color: #a855f7;
  --purple-light: rgba(168, 85, 247, 0.15);

  --radius-sm: 8px;
  --radius-md: 12px;
  --radius-lg: 16px;
  --radius-xl: 20px;
  --shadow-card: 0 4px 20px rgba(0, 0, 0, 0.25);
  --shadow-elevation: 0 10px 30px rgba(0, 0, 0, 0.35);
  --transition: all 0.2s ease-in-out;
}

[data-theme="light"],
body.light-theme {
  --bg-body: #f8fafc;
  --bg-card: #ffffff;
  --bg-card-subtle: #f1f5f9;
  --bg-input: #ffffff;
  --border-color: #cbd5e1;
  --border-focus: #0284c7;

  --text-primary: #0f172a;
  --text-secondary: #334155;
  --text-muted: #475569;

  --primary-color: #0284c7;
  --primary-hover: #0369a1;
  --primary-light: rgba(2, 132, 199, 0.12);

  --success-color: #059669;
  --success-light: rgba(5, 150, 105, 0.12);

  --warning-color: #d97706;
  --warning-light: rgba(217, 119, 6, 0.12);

  --danger-color: #dc2626;
  --danger-light: rgba(220, 38, 38, 0.12);

  --purple-color: #9333ea;
  --purple-light: rgba(147, 51, 234, 0.12);

  --shadow-card: 0 4px 15px rgba(0, 0, 0, 0.06);
  --shadow-elevation: 0 10px 25px rgba(0, 0, 0, 0.1);
}

/* --------------------------------------------------------------------------
   Layout base
   -------------------------------------------------------------------------- */
*, *::before, *::after {
  box-sizing: border-box;
  margin: 0;
  padding: 0;
}

body {
  font-family: var(--font-main);
  background-color: var(--bg-body);
  color: var(--text-primary);
  overflow-x: clip;
  width: 100%;
  max-width: 100%;
  min-height: 100vh;
  display: flex;
  flex-direction: column;
  line-height: 1.55;
  -webkit-font-smoothing: antialiased;
}

h1, h2, h3, h4, h5, h6,
.brand-title,
.panel-title,
.section-title {
  font-family: var(--font-heading);
  font-weight: 700;
  line-height: 1.25;
}

.mono {
  font-family: var(--font-mono);
}

/* Contenedor canónico */
.tool-layout {
  max-width: 1200px;
  margin: 1.5rem auto 3rem;
  padding: 0 1rem;
  width: 100%;
}

.tool-with-sidebar {
  display: flex;
  gap: 2rem;
  align-items: flex-start;
  width: 100%;
}

.tool-main-content {
  flex: 1 1 0%;
  min-width: 0;
  width: 100%;
}

.card-main {
  background: var(--bg-card);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-xl);
  padding: 1.75rem;
  box-shadow: var(--shadow-card);
  display: flex;
  flex-direction: column;
  gap: 2rem;
}

/* --------------------------------------------------------------------------
   Tarjeta de introducción y barra de herramientas
   -------------------------------------------------------------------------- */
.tool-intro-card {
  display: flex;
  flex-direction: column;
  gap: 1.25rem;
  padding-bottom: 1.5rem;
  border-bottom: 1px solid var(--border-color);
}

.tool-badge-row {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
  margin-bottom: 0.75rem;
}

.badge-pill {
  font-size: 0.75rem;
  font-weight: 600;
  padding: 0.3rem 0.75rem;
  border-radius: 9999px;
  display: inline-flex;
  align-items: center;
  gap: 0.35rem;
}

.badge-primary {
  background: var(--primary-light);
  color: var(--primary-color);
  border: 1px solid rgba(6, 182, 212, 0.3);
}

.badge-neutral {
  background: var(--bg-card-subtle);
  color: var(--text-secondary);
  border: 1px solid var(--border-color);
}

.tool-lead {
  font-size: 1.05rem;
  color: var(--text-secondary);
  line-height: 1.6;
}

.tool-action-bar {
  display: flex;
  flex-wrap: wrap;
  gap: 0.75rem;
}

.btn-sm {
  padding: 0.5rem 1rem;
  font-size: 0.875rem;
  font-weight: 600;
  border-radius: var(--radius-sm);
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 0.5rem;
  cursor: pointer;
  min-height: 40px;
  transition: var(--transition);
}

.btn-primary {
  background: var(--primary-color);
  color: #ffffff;
  border: none;
}
.btn-primary:hover {
  background: var(--primary-hover);
}

.btn-secondary {
  background: var(--bg-card-subtle);
  color: var(--text-primary);
  border: 1px solid var(--border-color);
}
.btn-secondary:hover {
  background: var(--bg-input);
  border-color: var(--text-muted);
}

.btn-outline-danger {
  background: transparent;
  color: var(--danger-color);
  border: 1px solid rgba(239, 68, 68, 0.3);
}
.btn-outline-danger:hover {
  background: var(--danger-light);
  border-color: var(--danger-color);
}

.btn-danger {
  background: var(--danger-color);
  color: #ffffff;
  border: none;
}
.btn-danger:hover {
  background: #b91c1c;
}

/* Barra de ejemplos típicos */
.sample-presets-bar {
  display: flex;
  align-items: center;
  flex-wrap: wrap;
  gap: 0.75rem;
  padding: 0.85rem 1.15rem;
  background: var(--bg-card-subtle);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-md);
}

.sample-presets-label {
  font-size: 0.85rem;
  font-weight: 600;
  color: var(--text-secondary);
}

.sample-presets-chips {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
}

.chip-btn {
  background: var(--bg-card);
  color: var(--text-primary);
  border: 1px solid var(--border-color);
  border-radius: 9999px;
  font-size: 0.8125rem;
  font-weight: 500;
  padding: 0.35rem 0.85rem;
  cursor: pointer;
  min-height: 34px;
  transition: var(--transition);
}

.chip-btn:hover {
  border-color: var(--primary-color);
  color: var(--primary-color);
}

/* --------------------------------------------------------------------------
   Workspace en 2 columnas (Formulario + Resultados)
   -------------------------------------------------------------------------- */
.calculator-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 1.75rem;
  align-items: start;
}

.card-panel {
  background: var(--bg-card-subtle);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-lg);
  padding: 1.5rem;
  display: flex;
  flex-direction: column;
  gap: 1.25rem;
}

.panel-header {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 0.75rem;
  padding-bottom: 0.85rem;
  border-bottom: 1px solid var(--border-color);
}

.panel-title {
  font-size: 1.15rem;
  display: flex;
  align-items: center;
  gap: 0.5rem;
  color: var(--text-primary);
}

.panel-title svg {
  color: var(--primary-color);
}

.panel-tag {
  font-size: 0.75rem;
  font-weight: 600;
  padding: 0.25rem 0.65rem;
  border-radius: var(--radius-sm);
  background: var(--bg-card);
  color: var(--text-muted);
  border: 1px solid var(--border-color);
}

.panel-tag.active {
  background: var(--primary-light);
  color: var(--primary-color);
  border-color: rgba(6, 182, 212, 0.3);
}

/* Formularios y controles */
.form-body {
  display: flex;
  flex-direction: column;
  gap: 1.15rem;
}

.form-group {
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
}

.group-label-row {
  display: flex;
  align-items: center;
  justify-content: space-between;
}

.form-label {
  font-size: 0.9rem;
  font-weight: 600;
  color: var(--text-primary);
}

.badge-optional {
  font-size: 0.7rem;
  font-weight: 500;
  padding: 0.15rem 0.5rem;
  border-radius: 4px;
  background: var(--bg-card);
  color: var(--text-muted);
  margin-left: 0.4rem;
  border: 1px solid var(--border-color);
}

.field-hint {
  font-size: 0.8rem;
  color: var(--text-secondary);
  line-height: 1.4;
}

/* Toggle de unidades mg/dL - umol/L */
.unit-toggle {
  display: inline-flex;
  background: var(--bg-card);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-sm);
  padding: 2px;
}

.unit-btn {
  background: transparent;
  border: none;
  font-size: 0.75rem;
  font-weight: 600;
  color: var(--text-secondary);
  padding: 0.25rem 0.65rem;
  border-radius: 6px;
  cursor: pointer;
  transition: var(--transition);
}

.unit-btn.active {
  background: var(--primary-color);
  color: #ffffff;
}

/* Inputs con sufijos */
.input-with-suffix {
  display: flex;
  align-items: center;
  background: var(--bg-input);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-sm);
  overflow: hidden;
  transition: var(--transition);
}

.input-with-suffix:focus-within {
  border-color: var(--border-focus);
  box-shadow: 0 0 0 3px var(--primary-light);
}

.input-with-suffix .form-control {
  flex: 1 1 0%;
  width: 0;
  min-width: 0;
  background: transparent;
  border: none;
  color: var(--text-primary);
  font-size: 1.05rem;
  font-weight: 600;
  padding: 0.65rem 0.85rem;
  min-height: 42px;
  outline: none;
}

.input-suffix {
  padding: 0 0.85rem;
  font-size: 0.85rem;
  font-weight: 600;
  color: var(--text-secondary);
  background: var(--bg-card);
  border-left: 1px solid var(--border-color);
  height: 42px;
  display: flex;
  align-items: center;
  white-space: nowrap;
}

/* Toggle pills de Sexo Biológico */
.gender-toggle-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 0.65rem;
}

.gender-option {
  cursor: pointer;
  display: block;
}

.gender-option input[type="radio"] {
  position: absolute;
  opacity: 0;
  pointer-events: none;
}

.gender-card {
  display: flex;
  align-items: center;
  justify-content: center;
  gap: 0.5rem;
  padding: 0.65rem 1rem;
  background: var(--bg-input);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-sm);
  color: var(--text-secondary);
  font-size: 0.95rem;
  font-weight: 600;
  min-height: 42px;
  transition: var(--transition);
}

.gender-option input[type="radio"]:checked + .gender-card {
  background: var(--primary-light);
  border-color: var(--primary-color);
  color: var(--primary-color);
}

.grid-2-col {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 0.85rem;
}

/* Resumen biométrico */
.biometrics-summary {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 0.5rem;
  padding: 0.85rem;
  background: var(--bg-card);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-sm);
}

.bio-stat {
  display: flex;
  flex-direction: column;
  gap: 0.15rem;
}

.bio-label {
  font-size: 0.725rem;
  color: var(--text-secondary);
}

.bio-val {
  font-size: 0.875rem;
  font-weight: 700;
  color: var(--text-primary);
}

/* --------------------------------------------------------------------------
   Panel de Resultados Clínicos (eGFR + KDIGO)
   -------------------------------------------------------------------------- */
.results-body {
  display: flex;
  flex-direction: column;
  gap: 1.25rem;
}

.gfr-main-card {
  background: var(--bg-card);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-md);
  padding: 1.25rem;
  display: flex;
  flex-direction: column;
  gap: 1rem;
}

.gfr-metric-header {
  display: flex;
  align-items: flex-start;
  justify-content: space-between;
  gap: 0.75rem;
}

.gfr-metric-label {
  display: block;
  font-size: 0.9rem;
  font-weight: 600;
  color: var(--text-primary);
}

.gfr-metric-sub {
  display: block;
  font-size: 0.775rem;
  color: var(--text-secondary);
}

.gfr-stage-badge {
  font-size: 0.8125rem;
  font-weight: 700;
  padding: 0.35rem 0.85rem;
  border-radius: 9999px;
  background: var(--success-light);
  color: var(--success-color);
  border: 1px solid rgba(16, 185, 129, 0.3);
  white-space: nowrap;
}

.gfr-metric-value-row {
  display: flex;
  align-items: baseline;
  justify-content: space-between;
  flex-wrap: wrap;
  gap: 0.75rem;
}

.gfr-number-display {
  display: flex;
  align-items: baseline;
  gap: 0.5rem;
}

.gfr-number {
  font-size: 3.25rem;
  font-weight: 800;
  line-height: 1;
  color: var(--text-primary);
}

.gfr-unit {
  font-size: 0.95rem;
  font-weight: 600;
  color: var(--text-secondary);
}

.gfr-status-pill {
  display: inline-flex;
  align-items: center;
  gap: 0.5rem;
  font-size: 0.875rem;
  font-weight: 600;
  color: var(--success-color);
}

.status-indicator {
  width: 10px;
  height: 10px;
  border-radius: 50%;
  background: currentColor;
}

/* Barra de estadios KDIGO interactiva */
.kdigo-stages-bar-wrapper {
  position: relative;
  margin: 1.25rem 0 0.5rem;
}

.kdigo-stages-bar {
  display: flex;
  height: 16px;
  border-radius: 9999px;
  overflow: hidden;
  background: var(--bg-card-subtle);
  border: 1px solid var(--border-color);
}

.stage-seg {
  flex: 1;
  display: flex;
  align-items: center;
  justify-content: center;
  font-size: 0.65rem;
  font-weight: 800;
  color: rgba(255, 255, 255, 0.9);
  transition: opacity 0.2s;
}

.stage-g1 { background: #10b981; }
.stage-g2 { background: #84cc16; }
.stage-g3a { background: #eab308; }
.stage-g3b { background: #f97316; }
.stage-g4 { background: #ef4444; }
.stage-g5 { background: #8b5cf6; }

.kdigo-marker {
  position: absolute;
  top: -10px;
  transform: translateX(-50%);
  display: flex;
  flex-direction: column;
  align-items: center;
  pointer-events: none;
  transition: left 0.3s cubic-bezier(0.4, 0, 0.2, 1);
}

.marker-pointer {
  width: 0;
  height: 0;
  border-left: 6px solid transparent;
  border-right: 6px solid transparent;
  border-bottom: 8px solid var(--text-primary);
}

.marker-label {
  font-size: 0.75rem;
  font-weight: 800;
  background: var(--text-primary);
  color: var(--bg-body);
  padding: 0.1rem 0.4rem;
  border-radius: 4px;
  margin-top: 18px;
}

.kdigo-bar-labels {
  display: flex;
  justify-content: space-between;
  font-size: 0.725rem;
  color: var(--text-secondary);
  padding: 0 2px;
}

/* Comparativa farmacológica con Cockcroft-Gault */
.metric-dual-card {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 1rem;
}

.metric-sub-item {
  background: var(--bg-card);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-md);
  padding: 1rem;
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
}

.sub-item-header {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 0.5rem;
}

.sub-item-title {
  font-size: 0.825rem;
  font-weight: 600;
  color: var(--text-secondary);
}

.sub-item-pill {
  font-size: 0.675rem;
  font-weight: 700;
  padding: 0.15rem 0.5rem;
  border-radius: 4px;
  background: var(--bg-card-subtle);
  color: var(--text-muted);
  border: 1px solid var(--border-color);
}

.sub-item-val-row {
  display: flex;
  align-items: baseline;
  gap: 0.4rem;
}

.sub-item-val {
  font-size: 1.65rem;
  font-weight: 800;
  color: var(--text-primary);
  line-height: 1.1;
}

.sub-item-unit {
  font-size: 0.8rem;
  color: var(--text-secondary);
  font-weight: 600;
}

.sub-item-desc {
  font-size: 0.775rem;
  color: var(--text-secondary);
}

/* Caja de explicación pedagógica */
.explanation-box {
  display: flex;
  gap: 1rem;
  background: var(--bg-card);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-md);
  padding: 1.25rem;
}

.explanation-icon {
  flex-shrink: 0;
  width: 40px;
  height: 40px;
  border-radius: 50%;
  background: var(--primary-light);
  color: var(--primary-color);
  display: flex;
  align-items: center;
  justify-content: center;
}

.explanation-content {
  display: flex;
  flex-direction: column;
  gap: 0.5rem;
}

.explanation-title {
  font-size: 1rem;
  color: var(--text-primary);
}

.explanation-text {
  font-size: 0.9rem;
  color: var(--text-secondary);
  line-height: 1.55;
}

.clinical-advice-box {
  background: var(--bg-card-subtle);
  border-left: 3px solid var(--primary-color);
  padding: 0.75rem 1rem;
  border-radius: 0 var(--radius-sm) var(--radius-sm) 0;
  font-size: 0.85rem;
  color: var(--text-secondary);
  line-height: 1.5;
  margin-top: 0.35rem;
}

.advice-heading {
  display: block;
  font-weight: 700;
  color: var(--text-primary);
  margin-bottom: 0.2rem;
}

/* --------------------------------------------------------------------------
   Sección: Seguridad de Medicamentos
   -------------------------------------------------------------------------- */
.section-meds-security {
  display: flex;
  flex-direction: column;
  gap: 1.5rem;
  padding-top: 1.5rem;
  border-top: 1px solid var(--border-color);
}

.section-meds-header {
  display: flex;
  flex-direction: column;
  gap: 1rem;
}

.section-title {
  font-size: 1.4rem;
  display: flex;
  align-items: center;
  gap: 0.6rem;
  color: var(--text-primary);
}

.section-title svg {
  color: var(--primary-color);
}

.section-desc {
  font-size: 0.95rem;
  color: var(--text-secondary);
}

.meds-filter-chips {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
}

.filter-chip {
  background: var(--bg-card-subtle);
  color: var(--text-secondary);
  border: 1px solid var(--border-color);
  border-radius: 9999px;
  font-size: 0.8125rem;
  font-weight: 600;
  padding: 0.45rem 1rem;
  cursor: pointer;
  min-height: 38px;
  transition: var(--transition);
}

.filter-chip:hover,
.filter-chip.active {
  background: var(--primary-light);
  border-color: var(--primary-color);
  color: var(--primary-color);
}

/* Parrilla de tarjetas de medicamentos */
.meds-cards-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 1rem;
}

.med-card {
  background: var(--bg-card-subtle);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-md);
  padding: 1.15rem;
  display: flex;
  flex-direction: column;
  gap: 0.75rem;
  transition: var(--transition);
}

.med-card.status-safe {
  border-left: 4px solid var(--success-color);
}

.med-card.status-warning {
  border-left: 4px solid var(--warning-color);
}

.med-card.status-danger {
  border-left: 4px solid var(--danger-color);
}

.med-card-header {
  display: flex;
  align-items: flex-start;
  justify-content: space-between;
  gap: 0.75rem;
}

.med-name-group {
  display: flex;
  flex-direction: column;
}

.med-name {
  font-size: 1.05rem;
  font-weight: 700;
  color: var(--text-primary);
}

.med-family {
  font-size: 0.775rem;
  color: var(--text-secondary);
}

.med-badge {
  font-size: 0.725rem;
  font-weight: 700;
  padding: 0.25rem 0.65rem;
  border-radius: 9999px;
  white-space: nowrap;
}

.med-badge.badge-safe {
  background: var(--success-light);
  color: var(--success-color);
  border: 1px solid rgba(16, 185, 129, 0.3);
}

.med-badge.badge-warning {
  background: var(--warning-light);
  color: var(--warning-color);
  border: 1px solid rgba(245, 158, 11, 0.3);
}

.med-badge.badge-danger {
  background: var(--danger-light);
  color: var(--danger-color);
  border: 1px solid rgba(239, 68, 68, 0.3);
}

.med-body {
  font-size: 0.875rem;
  color: var(--text-secondary);
  line-height: 1.5;
}

.med-footer {
  margin-top: auto;
  padding-top: 0.65rem;
  border-top: 1px solid var(--border-color);
  font-size: 0.8rem;
  display: flex;
  align-items: center;
  justify-content: space-between;
  color: var(--text-muted);
}

.meds-disclaimer-note {
  display: flex;
  align-items: flex-start;
  gap: 0.75rem;
  padding: 1rem 1.25rem;
  background: var(--warning-light);
  border: 1px solid rgba(245, 158, 11, 0.3);
  border-radius: var(--radius-md);
  font-size: 0.85rem;
  color: var(--text-primary);
  line-height: 1.5;
}

.meds-disclaimer-note svg {
  flex-shrink: 0;
  color: var(--warning-color);
  margin-top: 2px;
}

/* --------------------------------------------------------------------------
   Sección: Tabla KDIGO
   -------------------------------------------------------------------------- */
.section-kdigo-table {
  display: flex;
  flex-direction: column;
  gap: 1.25rem;
  padding-top: 1.5rem;
  border-top: 1px solid var(--border-color);
}

.table-responsive {
  width: 100%;
  overflow-x: auto;
  border: 1px solid var(--border-color);
  border-radius: var(--radius-md);
}

.kdigo-table {
  width: 100%;
  border-collapse: collapse;
  text-align: left;
  font-size: 0.875rem;
}

.kdigo-table th,
.kdigo-table td {
  padding: 0.85rem 1rem;
  border-bottom: 1px solid var(--border-color);
}

.kdigo-table th {
  background: var(--bg-card-subtle);
  font-weight: 700;
  color: var(--text-primary);
  font-size: 0.8rem;
  text-transform: none;
}

.kdigo-table tbody tr:hover {
  background: var(--bg-card-subtle);
}

.kdigo-table tbody tr.row-active {
  background: var(--primary-light);
  border-left: 4px solid var(--primary-color);
}

.badge-stage {
  font-size: 0.75rem;
  font-weight: 800;
  padding: 0.2rem 0.55rem;
  border-radius: 4px;
  color: #ffffff;
  display: inline-block;
}

.badge-g1 { background: #10b981; }
.badge-g2 { background: #84cc16; }
.badge-g3a { background: #eab308; }
.badge-g3b { background: #f97316; }
.badge-g4 { background: #ef4444; }
.badge-g5 { background: #8b5cf6; }

/* --------------------------------------------------------------------------
   Sección: Preguntas Frecuentes (FAQ)
   -------------------------------------------------------------------------- */
.section-faq {
  display: flex;
  flex-direction: column;
  gap: 1.25rem;
  padding-top: 1.5rem;
  border-top: 1px solid var(--border-color);
}

.faq-accordion {
  display: flex;
  flex-direction: column;
  gap: 0.75rem;
}

.faq-item {
  background: var(--bg-card-subtle);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-md);
  overflow: hidden;
  transition: var(--transition);
}

.faq-item[open] {
  border-color: var(--primary-color);
}

.faq-question {
  display: flex;
  align-items: center;
  justify-content: space-between;
  padding: 1.15rem 1.25rem;
  font-size: 0.95rem;
  font-weight: 600;
  color: var(--text-primary);
  cursor: pointer;
  list-style: none;
}

.faq-question::-webkit-details-marker {
  display: none;
}

.faq-icon {
  flex-shrink: 0;
  color: var(--text-muted);
  transition: transform 0.2s ease;
}

.faq-item[open] .faq-icon {
  transform: rotate(180deg);
  color: var(--primary-color);
}

.faq-answer {
  padding: 0 1.25rem 1.25rem;
  font-size: 0.9rem;
  color: var(--text-secondary);
  line-height: 1.6;
  display: flex;
  flex-direction: column;
  gap: 0.75rem;
}

.faq-answer ol,
.faq-answer ul {
  padding-left: 1.25rem;
}

.faq-answer li {
  margin-bottom: 0.35rem;
}

/* --------------------------------------------------------------------------
   Modales canónicos
   -------------------------------------------------------------------------- */
.modal-overlay {
  position: fixed;
  inset: 0;
  background-color: rgba(0, 0, 0, 0.85);
  backdrop-filter: blur(8px);
  z-index: 9999;
  display: flex;
  align-items: center;
  justify-content: center;
  padding: 1rem;
}

.modal-card {
  background: var(--bg-card);
  border: 1px solid var(--border-color);
  border-radius: var(--radius-lg);
  width: 100%;
  max-width: 620px;
  max-height: 90vh;
  display: flex;
  flex-direction: column;
  box-shadow: var(--shadow-elevation);
  animation: modalIn 0.2s ease-out;
}

.modal-card-sm {
  max-width: 440px;
}

@keyframes modalIn {
  from { opacity: 0; transform: scale(0.96) translateY(10px); }
  to { opacity: 1; transform: scale(1) translateY(0); }
}

.modal-header {
  display: flex;
  align-items: center;
  justify-content: space-between;
  padding: 1.25rem 1.5rem;
  border-bottom: 1px solid var(--border-color);
}

.modal-title-wrap {
  display: flex;
  align-items: center;
  gap: 0.65rem;
}

.modal-title {
  font-size: 1.15rem;
  color: var(--text-primary);
}

.text-warning {
  color: var(--warning-color);
}

.btn-close-modal {
  background: transparent;
  border: none;
  color: var(--text-muted);
  cursor: pointer;
  width: 40px;
  height: 40px;
  border-radius: var(--radius-sm);
  display: flex;
  align-items: center;
  justify-content: center;
  transition: var(--transition);
}

.btn-close-modal:hover {
  background: var(--bg-card-subtle);
  color: var(--text-primary);
}

.modal-body {
  padding: 1.5rem;
  overflow-y: auto;
  font-size: 0.925rem;
  color: var(--text-secondary);
  line-height: 1.6;
  display: flex;
  flex-direction: column;
  gap: 1.15rem;
}

.help-section h3 {
  font-size: 0.95rem;
  color: var(--text-primary);
  margin-bottom: 0.35rem;
}

.help-section ul {
  padding-left: 1.25rem;
}

.help-section li {
  margin-bottom: 0.3rem;
}

.modal-footer {
  display: flex;
  align-items: center;
  justify-content: flex-end;
  gap: 0.75rem;
  padding: 1.15rem 1.5rem;
  border-top: 1px solid var(--border-color);
  background: var(--bg-card-subtle);
  border-radius: 0 0 var(--radius-lg) var(--radius-lg);
}

/* --------------------------------------------------------------------------
   Hoja Imprimible Oficial A4 (.print-sheet)
   -------------------------------------------------------------------------- */
.print-sheet {
  display: none;
}

@media print {
  body {
    background: #ffffff !important;
    color: #111827 !important;
    font-size: 11pt !important;
  }

  .app-header,
  .tools-ad-banner-section,
  .tool-ad-sidebar,
  .card-main,
  .fijate-footer,
  .modal-overlay {
    display: none !important;
  }

  .tool-layout {
    max-width: 100% !important;
    margin: 0 !important;
    padding: 0 !important;
  }

  .tool-with-sidebar {
    display: block !important;
  }

  .print-sheet {
    display: block !important;
    width: 100% !important;
    max-width: 210mm !important;
    margin: 0 auto !important;
    padding: 15mm 20mm !important;
    background: #ffffff !important;
    color: #0f172a !important;
    line-height: 1.4 !important;
  }

  .print-header {
    display: flex;
    justify-content: space-between;
    align-items: flex-start;
    border-bottom: 2px solid #0f172a;
    padding-bottom: 12px;
    margin-bottom: 16px;
  }

  .print-title-box h1 {
    font-size: 16pt;
    margin-bottom: 4px;
    color: #0f172a;
  }

  .print-subtitle {
    font-size: 9.5pt;
    color: #475569;
  }

  .print-meta-box {
    text-align: right;
    font-size: 9pt;
    color: #334155;
  }

  .print-section {
    margin-bottom: 16px;
  }

  .print-sec-title {
    font-size: 11pt;
    font-weight: 700;
    margin-bottom: 8px;
    border-bottom: 1px solid #cbd5e1;
    padding-bottom: 4px;
    color: #0f172a;
  }

  .print-table {
    width: 100%;
    border-collapse: collapse;
    font-size: 9.5pt;
    margin-bottom: 8px;
  }

  .print-table td,
  .print-table th {
    padding: 6px 8px;
    border: 1px solid #e2e8f0;
    text-align: left;
  }

  .print-table th {
    background: #f8fafc;
    font-weight: 700;
  }

  .print-results-cards {
    display: flex;
    gap: 12px;
    margin-bottom: 12px;
  }

  .print-result-box {
    flex: 1;
    border: 1px solid #cbd5e1;
    border-radius: 6px;
    padding: 10px;
    display: flex;
    flex-direction: column;
    gap: 4px;
  }

  .print-res-label {
    font-size: 8.5pt;
    color: #64748b;
    font-weight: 600;
  }

  .print-res-val {
    font-size: 15pt;
    font-weight: 800;
    color: #0f172a;
  }

  .print-res-badge {
    display: inline-block;
    font-size: 8pt;
    font-weight: 700;
    padding: 2px 6px;
    border-radius: 4px;
    background: #e2e8f0;
    color: #0f172a;
    align-self: flex-start;
  }

  .print-text-box {
    border: 1px solid #cbd5e1;
    border-radius: 6px;
    padding: 10px;
    font-size: 9pt;
    color: #334155;
    background: #f8fafc;
  }

  .doctor-notes-area {
    border: 1px dashed #94a3b8;
    border-radius: 6px;
    height: 90px;
    position: relative;
    padding: 8px;
    margin-top: 6px;
  }

  .doctor-signature-box {
    position: absolute;
    bottom: 8px;
    right: 12px;
    font-size: 8.5pt;
    color: #475569;
  }

  .print-footer {
    border-top: 1px solid #cbd5e1;
    padding-top: 8px;
    margin-top: 16px;
    font-size: 7.5pt;
    color: #64748b;
    text-align: center;
  }
}

/* --------------------------------------------------------------------------
   Adaptaciones Responsivas (Móvil y Tablet)
   -------------------------------------------------------------------------- */
@media (max-width: 900px) {
  .calculator-grid {
    grid-template-columns: 1fr;
  }

  .meds-cards-grid {
    grid-template-columns: 1fr;
  }

  .card-main {
    padding: 1.25rem;
    gap: 1.5rem;
  }

  .biometrics-summary {
    grid-template-columns: 1fr;
  }
}

@media (max-width: 640px) {
  .tool-layout {
    margin: 1rem auto 2rem;
    padding: 0 0.75rem;
  }

  .card-main {
    padding: 1rem;
    border-radius: var(--radius-lg);
  }

  .tool-intro-card {
    gap: 1rem;
  }

  .tool-action-bar {
    flex-direction: column;
    width: 100%;
  }

  .tool-action-bar button {
    width: 100%;
  }

  .grid-2-col {
    grid-template-columns: 1fr;
  }

  .metric-dual-card {
    grid-template-columns: 1fr;
  }

  .gfr-number {
    font-size: 2.75rem;
  }

  .sample-presets-bar {
    flex-direction: column;
    align-items: stretch;
  }

  .sample-presets-chips {
    display: grid;
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .sample-presets-chips .chip-btn {
    text-align: center;
  }
}